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REVIEW ARTICLE
Year : 2018  |  Volume : 8  |  Issue : 1  |  Page : 6-12

Vitamin D, osteoporosis, and periodontal diseases


Department of Periodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India

Correspondence Address:
Dr. Akshara Mary Jacob
Department of Periodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijohs.ijohs_62_17

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1,25(OH)2D3 is a lipid-soluble vitamin which plays an important role in calcium metabolism. It also plays an important role in maintaining oral health through bone and mineral metabolism and innate immunity. Osteoporosis is loss of bone when there is an imbalance between bone formation and resorption. In osteoporosis, loss of bone density may render the host highly susceptible to periodontal destruction. Thus, there might be a possible association between Vitamin D, osteoporosis, and periodontitis characterized by loss of bone. Thus, understanding the underlying mechanisms of these associations will help improve prevention, diagnosis, and treatment of these diseases. A systematic search of the literature was conducted in the Cochrane Library, PubMed, Web of Science (ISI), Scopus, Copernicus, and Lilacs for full articles published until 2015 for this review.


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