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REVIEW ARTICLE
Year : 2020  |  Volume : 10  |  Issue : 2  |  Page : 74-78

Povidone-iodine: “The first line of defense” with potential anti-severe acute respiratory syndrome coronavirus-2 efficacy


1 Department of Orthodontics and Dentofacial Orthopaedics, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India
2 Department of Public Health Dentistry, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India
3 Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India

Correspondence Address:
Dr. Deepak Sharma
Department of Periodontology, H.P. Government. Dental College and Hospital, Shimla - 171 001, Himachal Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijohs.ijohs_24_20

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An outbreak of new coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) (coronavirus disease-19), has assumed the proportion of global pandemic having affected more than 200 countries and territories. In the absence of any specific treatment, efficient disinfectant and antiseptic products are useful to help prevent the spread of infection. Povidone-iodine formulations are well known for their broad-spectrum antimicrobial action and a remarkable safety profile. They have shown in vitro virucidal activity against different coronaviruses. Till the time there is a concrete clinical evidence of efficacy of antiseptic agents against the current coronavirus, povidone-iodine formulations can be used widely as first choice antiseptics as well as for preventive and prophylactic management of SARS-CoV2 infection. This review highlights the importance of Povidone-Iodine formulations in health-care settings as broad-spectrum antiseptic, especially because of their potential virucidal activity against SARS-CoV2.


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